After a run of bad luck, John (Steve Buscemi), a compulsive gambler, runs away from Las Vegas and toward a normal job and life. Taking a nondescript position in an auto insurance company in Albuquerque, he tries to get ahead in the straight world, amid the ever-present temptations of scratch-off lotto tickets.When his boss, Mr. Townsend (Peter Dinklage), asks John to accompany his top fraud debunker, Virgil (Romany Malco) on an investigation of a dubious car "accident" near Vegas, John sees an opportunity to get a promotion, though he's concerned about returning to the gambling game. Before leaving he becomes involved with his eccentric co-worker Jill (Sarah Silverman), a dalliance that has the potential to become a real relationship.